Mfge8 regulates enterocyte lipid storage by promoting enterocyte triglyceride hydrolase activity
نویسندگان
چکیده
منابع مشابه
Mfge8 regulates enterocyte lipid storage by promoting enterocyte triglyceride hydrolase activity.
The small intestine has an underappreciated role as a lipid storage organ. Under conditions of high dietary fat intake, enterocytes can minimize the extent of postprandial lipemia by storing newly absorbed dietary fat in cytoplasmic lipid droplets. Lipid droplets can be subsequently mobilized for the production of chylomicrons. The mechanisms that regulate this process are poorly understood. We...
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متن کاملInterferon- inhibits enterocyte migration by reversibly displacing connexin43 from lipid rafts
abnormal function of the gastrointestinal tract, hepatobiliary system, and pancreas. It is published 12 times a year (monthly) by the publishes original articles pertaining to all aspects of research involving normal or AJP-Gastrointestinal and Liver Physiology
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BACKGROUND AND AIMS When a high fat oral load is followed several hours later by further ingestion of nutrients, there is an early postprandial peak in plasma triacylglycerol (TG). The aim of this study was to investigate the location and release of lipid from within the gastrointestinal tract. METHODS Ten healthy patients undergoing oesopho-gastro-duodenoscopy (OGD) were recruited. At t=0, a...
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ژورنال
عنوان ژورنال: JCI Insight
سال: 2016
ISSN: 2379-3708
DOI: 10.1172/jci.insight.87418